Masaki Shimizu Selected Research

Macrophage Activation Syndrome

1/2021	Comparison of serum cytokine profiles in macrophage activation syndrome complicating different background rheumatic diseases in children.
12/2020	Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis during tocilizumab therapy.
1/2020	Tocilizumab modifies clinical and laboratory features of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
11/2019	Extensive serum biomarker analysis in patients with macrophage activation syndrome associated with systemic lupus erythematosus.
11/2019	Comparison of serum biomarkers for the diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
10/2019	Macrophage activation syndrome in neonates born to mothers with adult-onset Still's disease: Perinatal effect of maternal IL-18.
1/2019	Clinical significance of serum CXCL9 levels as a biomarker for systemic juvenile idiopathic arthritis associated macrophage activation syndrome.
1/2019	Cytokine profile of macrophage activation syndrome associated with Kawasaki disease.
2/2018	Role of plasma exchange, leukocytapheresis, and plasma diafiltration in management of refractory macrophage activation syndrome.
1/2018	Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis.

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Masaki Shimizu Research Topics

Disease

33	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 07/2022 - 09/2010
19	Macrophage Activation Syndrome 01/2021 - 09/2010
11	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 01/2021 - 09/2010
11	Infections 03/2020 - 01/2006
10	Hemolytic-Uremic Syndrome 12/2021 - 10/2012
8	Inflammation (Inflammations) 06/2022 - 12/2006
7	Neoplasms (Cancer) 01/2022 - 01/2019
6	Brain Diseases (Brain Disorder) 03/2020 - 12/2012
5	Fever (Fevers) 06/2022 - 12/2009
5	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2022 - 05/2013
5	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2022 - 02/2013
5	Proteinuria 01/2021 - 10/2005
4	Esophageal Squamous Cell Carcinoma 01/2022 - 01/2021
4	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2022 - 03/2011
4	Pain (Aches) 02/2021 - 01/2010
4	Adult-Onset Still's Disease 11/2020 - 06/2012
4	Arthritis (Polyarthritis) 04/2019 - 02/2013
3	Hemorrhage 01/2022 - 03/2013
3	Necrosis 02/2021 - 12/2012
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 02/2021 - 02/2013
3	IGA Glomerulonephritis (IGA Nephropathy) 01/2021 - 01/2014
3	Colitis 09/2016 - 05/2012
3	Pulmonary Hypertension 10/2011 - 01/2006
2	Dermatomyositis (Dermatopolymyositis) 12/2021 - 04/2014
2	Cytokine Release Syndrome 12/2021 - 02/2013
2	Hematuria 01/2021 - 10/2005
2	Chronic Renal Insufficiency 03/2020 - 10/2017
2	Sepsis (Septicemia) 01/2020 - 01/2011
2	Familial Mediterranean Fever (Periodic Disease) 01/2020 - 11/2010
2	Polyarteritis Nodosa (Periarteritis Nodosa) 01/2020 - 01/2017
2	Takayasu Arteritis (Arteritis, Takayasu's) 01/2019 - 08/2014
2	Human Influenza (Influenza) 01/2019 - 10/2012
2	Kidney Diseases (Kidney Disease) 10/2017 - 10/2016
2	Disease Progression 03/2017 - 01/2011
2	Hypothermia 01/2017 - 03/2011
2	Communicable Diseases (Infectious Diseases) 12/2016 - 01/2006
2	Tubulointerstitial nephritis and uveitis 05/2016 - 03/2013
2	Glomerulonephritis 04/2015 - 08/2010
2	Thrombocytopenia 1 01/2014 - 02/2013
2	Wiskott-Aldrich Syndrome 02/2013 - 08/2010
2	Liver Diseases (Liver Disease) 10/2011 - 12/2009
1	Hyperferritinemia 06/2022
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 01/2022
1	Necrotizing Enterocolitis 01/2022
1	COVID-19 01/2022
1	Chorioamnionitis 01/2022
1	Hyperglycemia 01/2022
1	2 X-Linked Lymphoproliferative Syndrome 01/2022

Drug/Important Bio-Agent (IBA)

18	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2010
18	CytokinesIBA 01/2021 - 09/2010
15	Interleukin-18 (Interleukin 18)IBA 01/2022 - 09/2010
13	InterleukinsIBA 12/2021 - 01/2011
9	Interleukin-6 (Interleukin 6)IBA 12/2021 - 01/2011
9	tocilizumab (atlizumab)FDA Link 12/2020 - 05/2012
7	Rituximab (Mabthera)FDA Link 01/2022 - 12/2006
6	Indicators and Reagents (Reagents)IBA 12/2021 - 01/2011
6	NeopterinIBA 01/2021 - 10/2012
6	EnzymesIBA 01/2020 - 12/2006
5	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2021 - 12/2012
4	ImmunosorbentsIBA 01/2020 - 06/2015
4	SteroidsIBA 04/2019 - 05/2012
3	Tacrolimus (Prograf)FDA LinkGeneric 07/2022 - 08/2014
3	BilirubinIBA 01/2022 - 05/2002
3	Antigen-Antibody Complex (Immune Complex)IBA 02/2021 - 08/2010
3	Angiopoietin-1IBA 12/2020 - 04/2016
3	Ferritins (Ferritin)IBA 01/2020 - 11/2016
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 01/2005
3	Biological ProductsIBA 04/2019 - 01/2018
3	Interleukin-33IBA 04/2019 - 05/2013
3	mizoribineIBA 10/2017 - 08/2014
2	Intravenous Immunoglobulins (IVIG)FDA Link 06/2022 - 10/2016
2	Infliximab (Remicade)FDA Link 06/2022 - 04/2019
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 11/2007
2	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2022 - 05/2013
2	baricitinibIBA 12/2021 - 01/2021
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2021 - 09/2016
2	Proteins (Proteins, Gene)FDA Link 09/2021 - 08/2010
2	Methylprednisolone FDA LinkGeneric 03/2020 - 07/2016
2	Shiga Toxin (Shigella Toxin)IBA 03/2020 - 09/2016
2	Monoclonal AntibodiesIBA 01/2020 - 01/2019
2	Leucine (L-Leucine)FDA Link 01/2019 - 09/2017
2	Immunosuppressive Agents (Immunosuppressants)IBA 06/2018 - 12/2006
2	Prothrombin (Factor II)IBA 03/2017 - 03/2013
2	AngiopoietinsIBA 02/2017 - 04/2016
2	Etanercept (Enbrel)FDA Link 01/2017 - 01/2015
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2009 - 01/2006
1	p38 Mitogen-Activated Protein KinasesIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	Excipients (Suspending Agents)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	DextrinsIBA 01/2022
1	acylcarnitineIBA 01/2022
1	GlucocorticoidsIBA 01/2022
1	X-Linked Inhibitor of Apoptosis ProteinIBA 01/2022

Therapy/Procedure

21	Therapeutics 06/2022 - 01/2005
3	Kidney Transplantation 12/2016 - 12/2006
2	Plasma Exchange 12/2021 - 02/2018
2	Induced Hypothermia 01/2017 - 06/2014
2	Aftercare (After-Treatment) 10/2016 - 01/2010
1	Extracorporeal Membrane Oxygenation 01/2022